News

The low-cost OCT system demonstrated by Sanghoon Kim, Prof. Wax, and the BIOS lab has continued to attract broad interest.  Though published in February 2018, was the 4th most downloaded OCT paper in Biomedical Optics Express in 2019.

Read "Design and implementation of a low-cost, portable OCT system"

A recent paper by Evan Jelly, Zach Steelman, and Prof. Wax demonstrated high quality OCT imaging of knee cartilage through an endoscopic borescope, a development that could aid arthroscopic surgery.  This work was one of the most downloaded articles from Optics Letters in November 2019.

Read "Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model"

The recent work first-authored by Ge Song is one of Translational Vision Science and Technology's most viewed articles of the month.  Click here to read "First Clinical Application of Low-Cost OCT."

Will Eldridge is our newest Doctor of Philosophy in Biomedical Engineering.  Will defended his thesis entitled "Development of optical tools for the assessment of cellular biomechanics," which describes a variety of new quantitative phase imaging methods he developed to investigate the mechanical properties of living cells.

Congratulations, Dr. Eldridge!

A newly published paper by Zach Steelman, Derek Ho, Ken Chu, and Professor Wax appearing in Optica has been ranked as the journal's third most downloaded item in the month of April 2019.  Entitled "Light-scattering methods for tissue diagnosis," this review article surveys and summarizes the recent applications of scattering-based optical techniques in clinical settings.

Three BIOS Lab graduate students became graduated students this weekend, receiving their diplomas to become newly minted Doctors of Philosophy.  Congratulations to Drs. Yang Zhao, Sanghoon Kim, and Derek Ho!

Congrats to Derek Ho, who successfully defended his Ph.D. thesis entitled "Development of Optical Technologies for Comprehensive Screening of Cervical Epithelial Health" on March 20, 2019!

It's defense season in the BIOS Lab, as Sanghoon Kim successfully defended his Ph.D. thesis on Thursday, July 19.

Congratulations, Dr. Kim!

Duke BME's newest Ph.D. is now Dr. Yang Zhao, who successfully defended his thesis project entitled "Deep tissue imaging with dual axis optical coherence tomography" on July 10, 2018.

Congratulations, Dr. Zhao!

Dr. Adam Wax traveled to China in May to deliver an invited talk at the 138th Optoelectronics Forum.  Speaking at the Wuhan National Laboratory for Optoelectronics (WNLO) to an audience of faculty and students from the WNLO, the Chinese Academy of Sciences, Wuhan University, and the Wuhan University of Technology, Dr. Wax presented the BIOS lab’s work on phase imaging of mechanical properties of living cells.

In appreciation for his presentation, Dr. Wax was given the Wuhan Optoelectronics Forum commemorative plaque.

Link to Story (in Chinese)

Master's student Haoran Zhang  has received a Student Research Fellowship from the Biomedical Engineering department for his project entitled “Computational Reconstruction of Angular Scattering Profiles Using a Single Multi-Mode Fiber.”

Congratulations, Haoran!

A new paper by Sanghoon Kim and co-authors from the BIOS Lab was the top-ranked download from the journal Biomedical Optics Express in February 2018.  The article, titled "Design and implementation of a low-cost, portable OCT system," describes how a fully functional spectral domain OCT system can be constructed for $7,200 in parts, far less expensive than pre-existing commercial OCT systems.

In March, the paper continued to attract widespread interest, remaining among the journal's top downloads in the #2 position.

Another work first-authored by Yang Zhao has been designated a Top Download.  In the month of January 2018, his paper was the 9th most downloaded article from the journal Biomedical Optics Express.  Entitled "Real-time speckle reduction in optical coherence tomography using the dual window method," this article describes a method to reduce speckle noise in OCT images using a single shot, and without requiring any hardware changes.

A recent paper by Yang Zhao and other members of the BIOS Lab has garnered a Top Download distinction.  Their paper, "Dual-axis optical coherence tomography for deep tissue imaging," which appeared in Optics Letters' 12th issue of 2017, was the journal's third most downloaded article during the month of June.

The article demonstrates that a new dual-axis OCT configuration is capable of imaging much deeper under skin than conventional OCT, and at much higher speeds than previous implementations of dual-axis OCT.

Congratulations to Yang for capturing the attention of the optics community!

One of our lab's recent research papers has caught the notice of the press.  An article in New Atlas highlights the findings of a Biophysical Journal paper, published by Ph.D. student Will Eldridge and Professor Wax along with co-authors Zach Steelman and Brianna Loomis.  This work describes how the stiffness of cells, which is a key metric in the study of cell function, can be measured in a novel way: by sensing the level of disorder within the cell using Quantitative Phase Microscopy.

Link to New Atlas media article

Link to Biophysical Journal research article

Congratulations to Jawad Hoballah!  Jawad was one of 11 Duke BME Master's students to receive the newly created Student Research Fellowship.

Pratt News

After three years at the BIOS laboratory, we say goodbye to Jason...

BIOS lab work by Jason Maher and Yang Zhao featured on Photonics.com

Recent papers on OCT & Raman spectroscopy and on spectroscopic OCT for characterizing burns

http://www.photonics.com/Article.aspx?AID=60579&PID=1&VID=138&IID=877

The OSA BIOMED congress in Hollywood, FL was great fun.

Presentations by our group included:

Clinical Detection of Cervical Dysplasia Using Angle-resolved Low Coherence Interferometry by Derek Ho

https://www.osapublishing.org/abstract.cfm?uri=Cancer-2016-CTh4A.2

Guidance of Angle-resolved Low Coherence Interferometry Using Co-located Optical Coherence Tomography on Rat Esophageal Tissue by Sanghoon Kim

 https://www.osapublishing.org/abstract.cfm?uri=Translational-2016-JTu3A.16

Toward the Assessment of Blood Oxygenation Using Multispectral Multiple Scattering Low Coherence Interferometry by Yang Zhao

https://www.osapublishing.org/abstract.cfm?uri=Cancer-2016-JM3A.24

October 13, 2015

Cambridge, MA

Nanoscale Imaging and Sensing of Live Cells

September 24-25, 2015

Bethesda, MD

Angle-resolved low coherence interferometry for the detection of cervical dysplasia in vivo