Research Overview

Active Research Topics

Retina Layers

Coherent Imaging of Alzheimer's Disease

Our lab aims to develop robust clinical imaging tools to extract quantitative changes in relevant biomarkers of disease, such as in Alzheimer’s disease.

fiber

Collecting Angle Resolved Scattering Through a Single Multimode Fiber 

We are currently developing an optomechanical system to achieve fast collection and reconstruction of angular scattering distributions using a single multimode fiber.

multimode

Coherence Domain Probes for Esophageal Imaging

We are now integrating a/LCI technology with our recently developed 3D printed paddle probes to provide a reading on dysplasia, as well as OCT images of Barrett’s esophagus, during a single endoscopic procedure.

OCT Ex Vivo Tissue

Dual-Axis Optical Coherence Tomography (DA-OCT)

DA-OCT exposes morphology otherwise undetected using conventional OCT using a distinct illumination and collection scheme to triangulate the signal to layers deep beneath the tissue surface.

Modified Robles

Spectroscopic Optical Coherence Tomography (SOCT)

By isolating narrowband regions of an OCT interferogram, spectroscopic optical coherence tomography (SOCT) allows for a more comprehensive assessment of tissues without additional necessary hardware.

Optical coherence tomography

Low Cost OCT

We seek to minimize the cost of optical coherence tomography (OCT) and provide comparable performance with commercial clinical systems by using inexpensive components such as uncooled SLD for the light source and liquid lens for the scanner.

QPI

Hyperspectral Holographic Cytometry

Quantitative phase cytometry is an effective label-free research tool used for high throughput examination of spatial and temporal properties of biological samples, by measuring the optical path delays of light.

quantitative phase imaging

Functional Phase Imaging

We are developing several methods to utilize quantitative phase imaging (QPI) for molecular, structural, and mechanical characterization of cells, including cancer cells and red blood cells (RBCs).