David Miller

Research Scientist

David studied biomedical engineering at Purdue University (BS '18) where he developed an interest in optical microscopy as an undergraduate research assistant in the Huang Group. After graduating, David joined the Functional Optical Imaging Lab (FOIL) at Northwestern University as a biomedical engineering graduate student (MS '20, PhD '23). At Northwestern, David focused on the development of visible-light optical coherence tomography (vis-OCT), and developed a novel extension of vis-OCT called vis-OCT fibergraphy, which enables in vivo visualization and quantification of retinal ganglion cell (RGC) axon bundles in the retina. In addition, David introduced techniques for improving noise suppression in OCT images. David joined the BIOS lab at Duke in 2023, where he focuses on research for low-cost OCT and spectroscopic OCT techniques.

Appointments and Affiliations

  • Research Scientist

Contact Information

  • Email Address: david.a.miller@duke.edu

Representative Publications

  • Lu, Kechao, Yirui Xu, David A. Miller, Wan Wang, Deven Gupta, Junjie Yao, and Adam Wax. “Indocyanine green (ICG) enhances penetration of 1300 nm optical coherence tomography imaging for in vivo murine skin.” Optics Letters 50, no. 17 (September 2025): 5226–29. https://doi.org/10.1364/ol.569764.
  • O’Kane, Erin C., Wan Wang, Robert E. Highland, David A. Miller, and Adam Wax. “Spectroscopic analysis of volumetric OCT data for the automated measurement of scatterer size.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 42, no. 9 (September 2025): 1344–53. https://doi.org/10.1364/josaa.569122.
  • Price, Hillel B., Ge Song, Wan Wang, Erin O’Kane, Kechao Lu, Evan Jelly, David A. Miller, and Adam Wax. “Development of next generation low-cost OCT towards improved point-of-care retinal imaging.” Biomedical Optics Express 16, no. 2 (February 2025): 748–59. https://doi.org/10.1364/boe.551625.
  • Fan, Weijia, Roman Kuranov, David A. Miller, Tingwei Zhang, Wei-Hong Yeo, Raymond Atkinson, Pengpeng Zhang, Cheng Sun, and Hao F. Zhang. “Swept-source visible-light optical coherence tomography.” Optics Letters 50, no. 3 (February 2025): 928–31. https://doi.org/10.1364/ol.544499.
  • Miller, D. A., Y. Xu, R. Highland, V. T. Nguyen, W. J. Brown, G. Hong, J. Yao, and A. Wax. “Enhanced penetration depth in optical coherence tomography and photoacoustic microscopy in vivo enabled by absorbing dye molecules.” Optica 12, no. 1 (January 20, 2025): 24–30. https://doi.org/10.1364/OPTICA.546779.