Congratulations to Dr. Zach Steelman!

June 6, 2020

Earlier this summer, Zach Steelman successfully defended his Ph.D. thesis entitled "Novel instrumentation for optical screening of epithelial dysplasia."

Zach defends his thesis via Zoom

Congratulations, Dr. Steelman!

Dr. Steelman

Low-cost OCT paper is a 2019 top download

December 19, 2019

The low-cost OCT system demonstrated by Sanghoon Kim, Prof. Wax, and the BIOS lab has continued to attract broad interest.  Though published in February 2018, was the 4th most downloaded OCT paper in Biomedical Optics Express in 2019.

Read "Design and implementation of a low-cost, portable OCT system"

2019 BOE top OCT downloads

OCT through a borescope garners top download honors

December 19, 2019

A recent paper by Evan Jelly, Zach Steelman, and Prof. Wax demonstrated high quality OCT imaging of knee cartilage through an endoscopic borescope, a development that could aid arthroscopic surgery.  This work was one of the most downloaded articles from Optics Letters in November 2019.

Read "Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model"

Optics Letters top downloads - Nov 2019

Clinical low-cost OCT paper catching eyes

July 23, 2019

The recent work first-authored by Ge Song is one of Translational Vision Science and Technology's most viewed articles of the month.  Click here to read "First Clinical Application of Low-Cost OCT."

TVST tweet

Congratulations to Dr. Will Eldridge!

July 23, 2019

Will Eldridge is our newest Doctor of Philosophy in Biomedical Engineering.  Will defended his thesis entitled "Development of optical tools for the assessment of cellular biomechanics," which describes a variety of new quantitative phase imaging methods he developed to investigate the mechanical properties of living cells.

Congratulations, Dr. Eldridge!

Dr. Will Eldridge

Light scattering review paper is an Optica top download

May 13, 2019

A newly published paper by Zach Steelman, Derek Ho, Ken Chu, and Professor Wax appearing in Optica has been ranked as the journal's third most downloaded item in the month of April 2019.  Entitled "Light-scattering methods for tissue diagnosis," this review article surveys and summarizes the recent applications of scattering-based optical techniques in clinical settings.

Optica top downloads - April 2019

Congrats to Yang, Sanghoon, and Derek!

May 13, 2019

Three BIOS Lab graduate students became graduated students this weekend, receiving their diplomas to become newly minted Doctors of Philosophy.  Congratulations to Drs. Yang Zhao, Sanghoon Kim, and Derek Ho!

Drs. Derek Ho, Sanghoon Kim, and Yang Zhao

Drs. Derek Ho, Yang Zhao, Adam Wax, and Sanghoon Kim

Congratulations to Dr. Derek Ho

April 11, 2019

Congrats to Derek Ho, who successfully defended his Ph.D. thesis entitled "Development of Optical Technologies for Comprehensive Screening of Cervical Epithelial Health" on March 20, 2019!

Dr. Derek Ho


Congratulations to Dr. Sanghoon Kim!

July 20, 2018

It's defense season in the BIOS Lab, as Sanghoon Kim successfully defended his Ph.D. thesis on Thursday, July 19.

Congratulations, Dr. Kim!

Dr. Sanghoon Kim

Congratulations to Dr. Yang Zhao!

July 11, 2018

Duke BME's newest Ph.D. is now Dr. Yang Zhao, who successfully defended his thesis project entitled "Deep tissue imaging with dual axis optical coherence tomography" on July 10, 2018.

Congratulations, Dr. Zhao!

Dr. Yang Zhao

Professor Wax goes to China

May 29, 2018

Dr. Adam Wax traveled to China in May to deliver an invited talk at the 138th Optoelectronics Forum.  Speaking at the Wuhan National Laboratory for Optoelectronics (WNLO) to an audience of faculty and students from the WNLO, the Chinese Academy of Sciences, Wuhan University, and the Wuhan University of Technology, Dr. Wax presented the BIOS lab’s work on phase imaging of mechanical properties of living cells.

In appreciation for his presentation, Dr. Wax was given the Wuhan Optoelectronics Forum commemorative plaque.

Dr. Wax presents an invited talk

Dr. Wax receives the Wuhan Optoelectronics Forum plaque

Link to Story (in Chinese)

Haoran Zhang receives fellowship

May 9, 2018

Master's student Haoran Zhang  has received a Student Research Fellowship from the Biomedical Engineering department for his project entitled “Computational Reconstruction of Angular Scattering Profiles Using a Single Multi-Mode Fiber.”

Congratulations, Haoran!

Haoran Zhang

Low-cost OCT paper is #1 download

March 15, 2018

A new paper by Sanghoon Kim and co-authors from the BIOS Lab was the top-ranked download from the journal Biomedical Optics Express in February 2018.  The article, titled "Design and implementation of a low-cost, portable OCT system," describes how a fully functional spectral domain OCT system can be constructed for $7,200 in parts, far less expensive than pre-existing commercial OCT systems.

BOE top downloads, February 2018

In March, the paper continued to attract widespread interest, remaining among the journal's top downloads in the #2 position.

Speckle reduction paper is a top 10 download in January

February 6, 2018

Another work first-authored by Yang Zhao has been designated a Top Download.  In the month of January 2018, his paper was the 9th most downloaded article from the journal Biomedical Optics Express.  Entitled "Real-time speckle reduction in optical coherence tomography using the dual window method," this article describes a method to reduce speckle noise in OCT images using a single shot, and without requiring any hardware changes.


BOE top downloads, January 2018

Dual-axis OCT paper is journal's #3 "Top Download"

July 6, 2017

A recent paper by Yang Zhao and other members of the BIOS Lab has garnered a Top Download distinction.  Their paper, "Dual-axis optical coherence tomography for deep tissue imaging," which appeared in Optics Letters' 12th issue of 2017, was the journal's third most downloaded article during the month of June.

The article demonstrates that a new dual-axis OCT configuration is capable of imaging much deeper under skin than conventional OCT, and at much higher speeds than previous implementations of dual-axis OCT.

Congratulations to Yang for capturing the attention of the optics community!

June 2017 OL Top Downloads


Quantitative phase imaging of cell disorder receives media attention

April 7, 2017

One of our lab's recent research papers has caught the notice of the press.  An article in New Atlas highlights the findings of a Biophysical Journal paper, published by Ph.D. student Will Eldridge and Professor Wax along with co-authors Zach Steelman and Brianna Loomis.  This work describes how the stiffness of cells, which is a key metric in the study of cell function, can be measured in a novel way: by sensing the level of disorder within the cell using Quantitative Phase Microscopy.

Link to New Atlas media article

Link to Biophysical Journal research article

A figure from the Biophysical Journal article

MS Student Jawad Hoballah Receives Inaugural Fellowship

April 7, 2017

Congratulations to Jawad Hoballah!  Jawad was one of 11 Duke BME Master's students to receive the newly created Student Research Fellowship.

Pratt News


Jawad Hoballah

We bid farewell to Jason

August 8, 2016

After three years at the BIOS laboratory, we say goodbye to Jason...

 Farewell Lunch Aug 2016

BIOS lab work featured at

May 12, 2016

Researchers are expanding interferometric techniques to improve medical diagnostics.

BIOS lab work by Jason Maher and Yang Zhao featured on

Recent papers on OCT & Raman spectroscopy and on spectroscopic OCT for characterizing burns


BIOS lab members attend OSA BIOMED congress

May 12, 2016

BIOS lab members boarding the conference party cruise

The OSA BIOMED congress in Hollywood, FL was great fun.

Presentations by our group included:

Clinical Detection of Cervical Dysplasia Using Angle-resolved Low Coherence Interferometry by Derek Ho

Guidance of Angle-resolved Low Coherence Interferometry Using Co-located Optical Coherence Tomography on Rat Esophageal Tissue by Sanghoon Kim

Toward the Assessment of Blood Oxygenation Using Multispectral Multiple Scattering Low Coherence Interferometry by Yang Zhao

Adam Wax gives the Modern Optics and Spectroscopy Seminar at MIT

October 11, 2015

October 13, 2015

Cambridge, MA

Nanoscale Imaging and Sensing of Live Cells


Derek Ho presents a/LCI cervix results at SPIE/NIH Biophotonics from Bench to Bedside conference

April 11, 2013

September 24-25, 2015

Bethesda, MD

Angle-resolved low coherence interferometry for the detection of cervical dysplasia in vivo