Current Members

Dr. Adam Wax, PhD, Principal Investigator

Dr. Adam Wax joined the faculty of the Biomedical Engineering department at Duke University as an assistant professor in 2002 and was promoted to associate professor in 2008. Dr. Wax received his Ph.D. in physics from Duke in 1999 and completed his postdoctoral training at MIT. His research interests include optical spectroscopy for early cancer detection, novel microscopy and interferometry techniques.

Office: CIEMAS 2571
Phone: (919) 660-5143
Email: a.wax@duke.edu

Tom Matthews, PhD, Postdoctoral Fellow

Tom received a B.A. in chemistry and a B.S. in biochemistry from the University of Vermont, and a PhD in chemistry from Duke University. His research foci in are low coherence interferometry and Raman spectroscopy.

Office: CIEMAS 2569
Phone: (919) 660-5588
Email: tem5@duke.edu
You "Leo" Li, PhD Candidate

Leo joined the BIOS Group in 2011. Since then, he has been working on the molecular imaging true-color spectroscopic optical coherence tomography (METRiCS OCT) system. In his first project, he extended the cellular/molecular imaging capabilities of the system using multispectral nanoparticles as contrast agents. Currently, his work is focused on the fabrication of low-cost fiber probes to enable endoscopic detection with the system. The system will then be used for early detection of colorectal dysplasia.

Office: CIEMAS 2569
Phone: (919) 660-5588
Email: leo.you.li@gmail.com
Tyler Drake, PhD, Postdoctoral Fellow

Tyler is a postdoctoral fellow developing novel microscopy techniques for clinical applications. He graduated from McDaniel College in 2006 with a BA in physics and obtained his MS in medical physics from Duke in 2008 with a concentration in radiation therapy. Specifically, Tyler is working on a multiplexed low coherence interferometry instrument for measuring microbicide thickness distribution.

Office: CIEMAS 2563
Phone: (919) 668-3942
Email: tyler.drake@duke.edu
Matt Rinehart, PhD Candidate

Matt is a second year Ph.D. student in Duke's biomedical engineering department. He graduated from Duke University with BSEs in biomedical engineering and electrical engineering in 2008. Matt is interested in novel interferometric microscopy techniques for both clinical applications and also basic cell biology research. Specifically, he works on transmission quantitative phase microscopy (QPM) and also endoscopic confocal microscopy.

Office: CIEMAS 2565
Phone: (919) 210-2051
Email: matt.rinehart@duke.edu
Han Sang Park, Masters Student

Han Sang is a first year Master's student in Duke's Biomedical Engineering program. He graduated from Duke University in 2012 with a BSE in BME. He is currently working on quantitative phase microscopy with a reflective interferometric chamber.

Office: CIEMAS 2567
Phone: (201) 803-9930
Email: kes32@duke.edu
Sanghoon Kim, PhD Candidate

Sanghoon is a first year Ph.D. student in biomedical engineering department. He graduated Duke University with dual majors in Biomedical engineering and physics. His current research involves application of 2 dimensional angle-resolved low-coherence interferometry (2D a/LCI) to measure angular distribution of scattered light to detect pre-cancerous cells in ex vivo retinal degeneration model in mice.

Office: CIEMAS 2567
Phone: (512) 922-1388
Email: sanghoon.kim@duke.edu
Kevin Seekell, PhD Candidate

Kevin joined the BIOS lab in 2009. He graduated from the University of Connecticut in with a BS in biomedical engineering. His works focuses on using immunolabeled plasmonic metal nanoparticles as contrast agents for molecular imaging of cancers. His early work involved using hyperspectral darkfield microscopy to identify three spectrally distinct nanoparticle species each targeting a different cell surface receptor. Scattering spectra obtained through this system give a relative measure of the expression level of each receptor, providing useful information needed for cancer treatment. His current work involves using immunolabeled gold nanorods to delineate the margins of glioblastoma brain tumors. Recent results have shown that gold nanorod labels bind to tumors with high sensitivity and specificity. They may be used as a tool for doctors to remove a majority of the tumor during surgical resection, improving a patient’s response to radiation and chemotherapy.

Office: CIEMAS 2563
Phone: (919) 668-3942
Email: kcs32@duke.edu
Spencer Lewis, Associate in Research

Spencer graduated magna cum laude from Duke University in 2012 with a BSE in biomedical engineering, a BS in neuroscience and a minor in chemistry. His research focuses on the wet lab protocols associated with nanoparticle optics and its biomedical applications, and in assisting in the design of a novel hybrid Raman/OCT system for quantifying the dynamics of antiretroviral drug transport. He also assists in data collection for experiments in dark-field microscopy and clinical trials of the a/LCI system, as well as general lab maintenance and miscellaneous tasks. Spencer plans to leave the group in August to attend medical school, by which point he hopes to have every square inch of linoleum in the BIOS lab blackened by scuff marks from his combat boots.

Office: CIEMAS 2569
Phone: (404) 909-6633
Email: spencer.lewis@duke.edu
Steve Yarmoska, Undergraduate Researcher

Steven Yarmoska has been a Pratt Undergraduate Research Fellow in the BIOS Laboratory since January 2012. He is a member of the Tau Beta Pi engineering honor society will graduate with Distinction from Duke University in May 2013 with a degree in Biomedical Engineering and minors in Chemistry and Biology. Steven has assisted on recent clinical and laboratory applications of a/LCI. His most recent work, a collaborative effort involving the Shared Materials Instrumentation Facility, aims to develop accurate, robust, and biologically-relevant calibration phantoms for 2D a/LCI instruments

Office: CIEMAS 2565
Phone: (919) 660-5211
Email: syarmoska@gmail.com

Past Members

 Hillel Price
 Robert N. Graf, Ph.D
 Kelly Braun, MA
 Derrick Chou, MS
 Adam Curry, Ph.D.
 Justin Keener, MS
 John Pyhtila, Ph.D.
 William J Brown, Ph.D.
 Kevin Chalut, Ph.D.
 Mark Gu
 Ryan Kobylarz
 Eric Su
 Natan "Nati" Shaked, Ph.D.
 Jeff Boyer
 Tilden Hagan
 David Wagner
 Shuping Koh
 Adam Karpinski
 Jesse Sandberg
 Cyrus Amoozegar
 Hyun-Joong Kim
 Karen Schroeder
 Steve Gebhart, Ph.D.
 Matt Crow, Ph.D.
 Mike Giacomelli, Ph.D
 Yizheng Zhu, Ph.D

 William Hwang
 Sidhartha Palani
 Michele Coleman
 Jenna Woodburn
 Rae Luan
 Varun Gokarn
 Walter Li
 Kyu Hyun Kim, MS
 Shwetadwip Chowdhury
 Jeffrey LaCroix, Ph.D.
 Francisco "Paco" Robles, Ph. D.
 Neil Terry, Ph.D.